Our research explores the complex interactions among plants, microorganisms, and their environments, with the goal of developing innovative and sustainable solutions for agriculture, environmental protection, and One Health. The research activities of our laboratory span plant biotechnology, microbiology, microbial ecology, environmental biotechnology, synthetic biology, and systems biology, addressing fundamental and applied challenges related to ecosystem functioning, plant and environmental health, antimicrobial resistance, and the sustainable use of biological resources. To advance these objectives, we employ state-of-the-art technologies including next-generation sequencing (NGS), multi-omics, genome editing, bioinformatics, machine learning, molecular and cellular engineering and bioassays, including mammalian cell-based experimental systems. Our research also focuses on the development of microbial inoculants and plant biofactories for the sustainable production of high-value biomolecules, contributing to the transition towards a resilient bioeconomy and more sustainable agricultural and industrial systems.

The spread of pathogens and antimicrobial resistance (AMR) represents a significant public health concern.

Beneficial fungal endophytes are microorganisms that live within plant tissues without causing disease, forming intimate and often long-lasting associations with their hosts.

Toxicity of pesticides onto non target organisms is an indispensable part of the pesticide regulatory framework.

Functional metagenomics constitute a powerful tool for the discovery of novel enzymes of biotechnological interest.

Soil constitutes the major sink of organic pollutants where the end-up intentionally (pesticides) or unintentionally

Identification of genetic markers that predict response to therapy enabling personalized treatment approaches.

Plant symbioses with soil microorganisms, particularly arbuscular mycorrhizal (AM) fungi and nitrogen-fixing rhizobia, are among the most widespread and ecologically significant mutualistic interactions in terrestrial ecosystems.

Plant-associated microorganisms exhibit diverse lifestyles, ranging from pathogenic to mutualistic and commensal interactions.

Plants produce a vast diversity of compounds collectively known as specialized (or secondary) metabolites. Our research focuses on the specialized (secondary) metabolism in plants, and particularly in the biosynthesis and functional role of triterpenes.

This research project focuses on the identification of bioactive compounds derived from plants and the evaluation of their anticancer potential.

Biopesticides constitute the next big challenge of modern agriculture to support the growing global food

Our applied research focuses on the development of RNA-based technologies for sustainable agriculture and next-generation crop protection.

Cross-kingdom RNA interference (ck-RNAi) is a biological communication process in which small RNA (sRNA) molecules move between organisms from different kingdoms, such as plants and fungi, to regulate and silence specific genes.

Nitrification is the rate-limiting step of N cycling. It is performed in two successive steps by ammonia oxidizing bacteria (ΑΟΒ) or archaea (ΑΟΑ)

Our successful story

Key figures that reflect the laboratory’s activity, scientific output and contribution to research and education.

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